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How to Choose Between Tirzepatide and Semaglutide Heres a simple decision guide we use at Potere Health MD: Semaglutide (Wegovy) May Be Best If You Want: A highly effective, well-studied GLP-1 medication A more affordable option A great starting point if youre new to weight-loss injections Strong appetite reduction with fewer upfront costs Tirzepatide (Zepbound) May Be Best If You Want: Maximum possible weight loss Faster and stronger appetite control A medication with dual action (GLP-1 + GIP) A good option after semaglutide plateaus You tolerate GLP-1 therapy well and want a next-level result The best medication depends on your goals, medical history, budget, and response

Skipping titration steps or increasing doses ahead of schedule amplifies the metabolic stress that triggers telogen effluvium

Your healthcare provider may recommend anti-nausea medications or adjust your dosing schedule to improve tolerance

Week 1-2: the bridge period Residual tirzepatide still provides significant activity
This metabolic stress is thought to be the primary driver of hair shedding, rather than any direct action of the drug on hair follicles

It is also essential to allow for a washout period , depending on your previous dose of semaglutide and your providers assessment
