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Risk of diabetic retinopathy and diabetic macular oedema with sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in type 2 diabetes: a real-world data study from a global federated database

The evidence on intermittent use of GLP-1 receptor agonists is limited, and decisions should be individualized based on your specific health needs and response

[DOI] [PubMed] [Google Scholar] 839.Femminella G.D., Frangou E., Love S.B., Busza G., Holmes C., Ritchie C

Regarding the effect of GLP-1 on vascular endothelium, numerous in vitro studies and animal studies showed either nitric oxide-dependent or -independent vasodilative effects [121415192021]

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But allowing unauthorized manufacturers to mass market GLP-1 knockoffs outside FDA safeguards creates significant patient safety risks and undermines trust in the healthcare system. GLP-1 medicines such as semaglutidemarketed as Ozempic and Wegovyand tirzepatidesold as Mounjaro and Zepboundhave become among the most widely used diabetes and weight loss treatments