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Recurrence with dose escalation When following the recommended titration schedule, patients may experience a temporary return of thirst with each dose increase

If you take oral semaglutide with food or eat too soon afterward, your body may absorb less of the medication

Need for a different delivery route (sublingual when you cannot self-inject)

I was in bed for most of the day several days in a row

Continue taking the medication as directed, and our medical team will adjust your dose as needed to optimize your weight loss

Key genetic markers include GLP1R rs6923761 (affecting GLP-1 receptor sensitivity), GIPR rs1800437 (influencing glucose-dependent insulin secretion), and FTO rs9939609 (related to appetite regulation and fat mass)