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GLP-1 receptor agonists require regular administrationweekly for semaglutide and tirzepatideto maintain steady-state drug levels

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Indexes of insulin sensitivity ( a , b ), insulin secretion ( c ) and beta cell function ( d ) in PLIS with response defined as return of 60min glucose during the OGTT below 155 mg/dL

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For those who are prescribed a GLP-1 receptor agonist, its important to note that theyll be most effective when combined with lifestyle changes