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November 14, 2025

In men with obesity-related functional hypogonadism, excess fat tissue can increase aromatase activity, converting more testosterone into estradiol, while inflammation and insulin resistance further suppress the HPG axis

Educate all patients on precipitating factors (such as insulin dose reduction or missed insulin doses, infection, reduced caloric intake, ketogenic diet, surgery, dehydration, and alcohol abuse) and symptoms of ketoacidosis (including nausea, vomiting, abdominal pain, tiredness, and labored breathing)

Change Out of Wet Bathing Suits Wearing sweaty, tight-fitting, or wet swimwear for prolonged periods may increase your risk for yeast infections

[1] Healthcare providers may need to adjust the dosages of these concomitant medications to mitigate the risk of hypoglycemia