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Other oral compounds like CT-996 / RG 6652 showed a clinically meaningful weight reduction of 6-7% in four weeks among participants without T2D, and GSBR-1290 has demonstrated favourable safety, tolerability and efficacy results

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The metabolic rate of GLP-1R KO mice was significantly slower than that of WT mice (p=0.0345, WT mice 0.023350.057mM/min, GLP-1R KO mice 0.019980.07mM/min)
