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Lancet Diabetes Endocrinol, 7 , 356367

( B ) The intrinsic potency of TZP ( n = 22) is approximately 18-fold lower than GLP-1(7-36) ( n = 57)

52 The infusion of active GIP tends to suppress injury-induced neointimal hyperplasia and vascular cell proliferation, thus potentially inhibiting restenosis after angioplasty
Understanding how this dual engagement works at the receptor and cellular level is increasingly relevant for both clinicians and drug discovery teams designing the next generation of incretin mimetics

Adverse events caused treatment discontinuation in 4.3%, 7.1%, 6.2%, and 2.6% of participants receiving 5-mg, 10-mg, 15-mg tirzepatide doses and placebo, respectively [49]

doi: 10.1111/j.1463-1326.2011.01364.x 109 DunganKMPovedanoSTForstTGonzlezJGGAtissoCSeallsWet al
