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Direct Myocardial Effects Although the presence of functional GLP-1 receptors on human ventricular cardiomyocytes remains a matter of debate, preclinical studies suggest potential direct cardioprotective effects

A whole ecosystem has formed around GLP-1 demand

This is the FDA choking off the supply of the physical material needed to make the product

In a comparison of weekly versus daily GLP-1RA, weekly GLP-1RA users had a significantly higher rate of adherence to treatment than daily GLP-1RA users did (79.9% versus 66.6%, respectively

The new 7.2 mg dose added one notable signal: about 22% of patients reported dysesthesia (tingling or altered skin sensation)

Obes Rev (2022) 23:e13372
