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However, rapid weight loss can temporarily change the biomechanics of the spine

GLP-1 receptor agonists: Beyond their pancreatic effects

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There has been a worldwide shortage of these drugs, with many companies offering compounded versions (mixed by an independent pharmacy and adding other components such as vitamins) versus getting the FDA-approved medication directly from the manufacturer

Decades of research have highlighted the clinical demerits of abnormally high body weight (BW), with BMIs exceeding 30 kg/m 2 and 40 kg/m 2 correlated with decreased life expectancies of three and 10 years, respectively

The improved glucose metabolism is mainly due to three closely interacting factors: 1) rapid absorption of glucose from the intestine giving rise to high post-prandial glucose responses, 2) a consequent exaggerated secretion of GLP-1 that act on the -cells, and 3) radically improved hepatic and subsequently peripheral insulin sensitivity [226]