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Just like Ozempic, Wegovy, and similar drugs, supplements like berberine may also cause digestive issues, including upset stomach and bloating, as well as serious drug interactions

doi: 10.1172/jci.insight.159863

Heart disease and uncontrolled high blood pressure add another layer of risk

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Combining these medications with GIPR antagonist medications, glucagon receptor agonists, GLP-2R agonists, or agonists of amylin receptors might enhance their benefits

Examples of these instruments include the Patient Assessment of Gastrointestinal Disorders Symptoms questionnaire, Gastroparesis Cardinal Symptom Index and Diabetes Bowel Symptom Questionnaire
