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soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

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soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

Results from Phase 3 trials have put a new drug called Retatrutide (sometimes called Reta) back in the news again.

soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

Summary: At the end of the trials 72 weeks, the high dose combination arm had

soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

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soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

When this milieu is perturbed, brain hyperglycemia, brain glucotoxicity, and brain insulin resistance can ensue and interfere with insulin signaling, a key pathway to cognitive function and neuronal integrity

soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

tirzepatide and semaglutide exceeded 10% TBWL and showed the most favourable glycaemic effects

soul trial oral semaglutide cardiovascular outcomes results 2024 nejm found to lower risk of heart failure events in people with type 2 diabetes SOUL (Semaglutide cardiOvascular oUtcomes triaL)

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