examples of glp 1 receptor agonists Current Insights, Advantages and Challenges Small Molecule Glucagon-like Peptide Agonists: A Scoping Review Frontiers | GLP−1 receptor agonists

Evidence based on recent studies Initially, cases of intestinal obstruction associated with GLP-1 RAs were reported by the European Medicines Agency (EMA) in 2013 [9], and this safety signal is currently being monitored by the United States (US) FDA

10/16/23 This material is for informational use only

Lately, attention has been directed to GIP and its role in glucose homeostasis, and efforts are underway to develop compounds that mimic GIP actions in addition to those of GLP-1

doi:10.3390/jcm14113812 10.Jastreboff AM, Ryan DH, Bays HE, et al

Notably, GLP-1RAs slow the transit time of the gastrointestinal (GI) tract and suppress appetite, which could displace nutrient intake and result in mineral and vitamin deficiencies

Mazdutide Mazdutide is another GLP-1/glucagon dual receptor agonist, developed by Innovent Biologics