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The incretin hormone glucagon-like peptide 1 (GLP-1) has been implicated in the gutrenal axis and incretin-based therapies might reduce the burden of diabetic kidney disease

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I was expecting to see more GI side effects with the higher dose, but it wasn't too much higher--70.8% at 7.2 mg vs 61.2% at 2.4 mg vs 42.8% with placebo, mostly mild an self-limited

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There is no doubt that GLP-1 medications for weight loss are changing the game in terms of how we view and treat obesity, weight loss and even plastic surgery