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Why it matters: A larger research signal is not the same as a settled treatment option

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27,28 By slowing degradation of GLP-1, these DPP-IV inhibitors enhance the action of endogenous GLP-1 to activate vagal sensory neurons that compose the hepato-portal glucose sensor

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The 2025 Kokkorakis pharmacology review framed both compounds within the emerging-obesity-pharmacotherapy landscape (PMID 39952695)
