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Following the prescribed titration schedule (starting low and increasing gradually) minimizes these effects and, by extension, minimizes the dehydration that drives UTI risk

Interestingly, weight changes were not correlated with changes in Hurley stage, BDI, or inflammatory markers [34]

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dose escalation may be delayed by 1 additional week if necessary: Week 1: Inject 0.6 mg subcutaneously once a day Week 2: Inject 1.2 mg subcutaneously once a day Week 3: Inject 1.8 mg subcutaneously once a day Week 4: Inject 2.4 mg subcutaneously once a day Week 5: Inject 3 mg subcutaneously once a day Maintenance dose : 3 mg subcutaneously once a day-If maintenance dose is not tolerated, discontinuation is recommended