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10.1016/S2213-8587(20)30038-3 21 HansenB

The combination of reduced oral intake from appetite suppression and fluid losses from gastrointestinal symptoms creates a vulnerable period, especially during the first 812 weeks of therapy or following dose increases

Liraglutide Both liraglutide and retatrutide are studied for other potential uses apart from obesity and T2D management

Mistake #2: Going Too Low on Calories The problem: With appetite suppression, some people eat only 800-1,000 calories daily, thinking "if less is good, even less is better." Why it matters: Extreme calorie restriction triggers metabolic adaptation, increases muscle loss, causes fatigue, and makes weight regain more likely when you stop the medication