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Cardiovascular devices: 2 The impact on cardiology practice remains to be seen, although typically conservative approaches make it likely that stents, pacemakers, and other devices will continue to be widely used

Special considerations for specific populations Switching with type 2 diabetes If you are using semaglutide for both diabetes management and weight loss, the switch to tirzepatide requires extra monitoring

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In addition to the US FDA approved GLP-1RAs, there are GLP1/glucagon dual agonists (Cotadutide, BI 456906), GIP/GLP1 dual agonists (Tirzepatide, GIP/GLP peptide I and II), GIP/GLP1/glucagon tri-agonists (HM15211, GGG tri-agonist) and GLP1R agonists (Efpeglenatide, Rybelsus) currently in phase 1- III clinical trials for T2D, obesity, and NASH (MASH) treatments (12)

Knowing how to take GLP-1 drops is more than just following instructions

As of late December 2025, Health Canada had nine active applications from companies that want to sell generic semaglutide