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Diabetic encephalopathy is a chronic neurodegenerative complication of diabetes mellitus characterized by cognitive decline, neuroinflammation, oxidative stress, and impaired insulin signaling

A comprehensive review of the literature was conducted to examine the etiology of HFpEF, the role of endothelial dysfunction, and the effects of GLP-1R agonists on endothelial function and heart failure outcomes

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Division of Cardiothoracic Surgery, Department of Surgery, The Warren Alpert Medical School of Brown University OPEN ACCESS PUBLISHED: 30 November 2025 CITATION: Zheng,

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Observational studies in autoimmune rheumatic diseases (ARDs) such as rheumatoid arthritis and systemic lupus erythematosus indicate