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To view digital features for this article go to Introduction Obesity (defined as a body mass index [BMI] 30 kg/m 2 in adults [1]) is a major health concern in the USA [2] and is associated with multiple complications, including cardiovascular disease, type 2 diabetes, and osteoarthritis [3,4,5,6,7,8]

Patients who experience inflammation of the pancreas (pancreatitis), gallbladder problems (including gallstones), symptoms of pancreatitis or gallstones, low blood sugar, acute kidney injury, diabetic retinopathy (damage to the eyes & retina), increased heart rate, and suicidal behavior or thinking

The year 2021 witnessed a staggering 529 million diagnosed cases of diabetes, with projections indicating a substantial increase to over 1.31 billion cases by the year 2050 ( GLP-1 RAs are experiencing expanded global utilization and favorable market potential