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In head-to-head clinical trials, the tirzepatide group often showed greater weight reduction and better blood sugar control compared to the semaglutide group at the doses studied

[DOI] [PubMed] [Google Scholar] 912.Kanoski S.E., Ong Z.Y., Fortin S.M., Schlessinger E.S., Grill H.J
More recently, in March 2024, Wegovy was This approval followed promising results from novo Nordisks SELECT trial, which followed 17,604 adults with obesity or overweight and cardiovascular disease but no history of diabetes

The standard classification of diabetes as type 1, type 2 and gestational diabetes mellitus (GDM) as introduced by the American Diabetes Association (ADA) in 1997 remains the best-accepted and adopted by ADA (4)

9-11 This effect on weight may provide motivation to patients to continue additional weight loss strat-egies, as they are no longer competing against their insulin to lose weight

Maalouf is funded by the National Institutes of Health (Grants R01-DK081423 and R01-DK115703)