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(2001) mutated W33 ECD to Ser (the human to rat GLP-1R substitution), as well as to various other residue types, showing that there was no effect on GLP-1 albeit that the affinity and potency values were not given for the peptide ligands used
These drugs differ in strength, dosing schedules and approved uses

doi: 10.1016/j.ejphar.2012.12.012 143 McCleanPLJalewaJHolscherC

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If your body becomes adjusted to the maximum dose of phentermine so that its effects are experienced less strongly, the maximum dose should not be exceeded in an attempt to increase the effect