glp 1 receptor agonists are contraindicated in GLP-1 transforming diabetes care by improving blood sugar control, supporting weight loss, and reducing cardiovascular risk when used appropriately. Evidence-based therapy selection, correct dosing, and patient counseling are GLP-1 receptor agonists | How

The 2025 review also reported that in a large retrospective study of 461,328 adults initiating GLP-1 therapy, over 22% developed at least one nutritional deficiency within 12 months, with vitamin D the most common deficiency identified

Among the observational studies 39,45,46,49,50,51 comprised by the meta-analyses, two are worth a separate mention

The intestines adapt to changed motility patterns

Global prevalence of pancreatic cystic lesions in the general population on magnetic resonance imaging: a systematic review and meta-analysis

Clearly, these observations must be taken into account when prescribing DDP-4is, always with a view to a targeted therapy that is increasingly designed to meet the specific needs of the individual patient

SURMOUNT-3 evaluated the efficacy and safety of tirzepatide compared to placebo for 72 weeks after a 12-week intensive lifestyle intervention lead-in period that included a low-calorie diet and exercise