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In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.

This GLP1 analog has shown promising results in improving cardiovascular outcomes

It is a narrow tube resembling a worm and is named after the Latin word "vermiform" which means worm-shaped

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For its cardiovascular benefits, semaglutide is believed to reduce atherosclerosis progression by decreasing gut permeability and inflammation[2]