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Those in the trial that did experience negative side effects did so at the same rate and consistency as those previously reported for injectable GLP-1 drugs and Eli Lilly said it "was consistent." The drugmaker said the most commonly reported negative side effects were mild to moderate gastrointestinal-related symptoms, such as nausea, constipation, indigestion, diarrhea and vomiting

And if they do help you, you may have to take them indefinitely or risk regaining most of the weight you lost

Molecules 22 , 1282 (2017)

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Symptoms may include dull, throbbing head pain

The thyroid neoplasm and suicidal ideation signals that are detected for semaglutide do not reach the disproportionality threshold for tirzepatide