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Discussion: These findings identify a subset of thyroid carcinomas with high GLP-1R expression, most pronounced in metastatic disease, which are accompanied by distinct genetic and immunological profiles
GLP-1 agonist drugs like Ozempic work by stimulating the GLP-1 receptor in the body, which helps increase insulin secretion, reduce glucagon release, slow down stomach emptying, and promote a feeling of fullness
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Antagonistic targeting of the histamine H3 receptor decreases caloric intake in higher mammalian species
