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GLP-1 based therapies led to statistically significant reductions in the serum levels of brain natriuretic peptide (40.16 [51.50, 28.81]

Main text Within this review, we provide an overview of the intricate interplay between chronic inflammation of the adipose tissue and the hypothalamus and the development of obesity

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Moreover, the efficacy of these drugs in MC4R KO mice aligns with clinical studies, indicating that MC4R KO mice serve as a reliable animal model for obesity research.

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