glp-1 agonists mechanism of action Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms Mechanisms of Action and Therapeutic
Description
BMJ Glob Health

48 h) significantly reduces high glucose (HG)-stimulated production of fibronectin, collagen type IV, and -smooth muscle actin in human mesangial cells

Additionally, empagliflozin has exhibited inhibitory effects on diverse tumor types, including pancreatic and prostate cancers [32]

GLP-1 and GLP-1R additionally have a substantial presence in the brain

References: New CDC Data Show Adult Obesity Prevalence Remains High CDC Newsroom 2024

Incidence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts
