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Description
In a cross-sectional study on 109 children with PWS aged 218 years (50 with obesity and 59 without obesity), and 96 controls with simple obesity matched for age, gender and BMI, it was shown that children with PWS without obesity showed significantly lower frequency of hypertension (12%) than subjects with PWS and obesity (32%), and controls with simple obesity (35%), suggesting the crucial role of obesity rather than the syndrome per se in the absence of excessive weight [37]

Funding This work was supported by the National Library of Medicine (5T15LM007124-24 to SJG)

Vargas EJ, Rizk M, Gomez-Villa J, Edwards PK, Jaruvongvanich V, Storm AC, et al
The dose may be increased again to 14 mg once daily if additional glycemic control is needed after 30 days of treatment with the 7-mg dose

The body composition cost, hair loss signal, and gastrointestinal tail are unchanged

In the end all 3 arms that were originally on retatrutide from the beginning were tightly clustered between 28 and 30% body weight loss
