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and M.Z.) and the Innovative Research Team of High-Level Local Universities in Shanghai (to M.Z.)

Using pharmacological agents with cardiovascular and renal benefits, including renin-angiotensin system inhibitors and sodium-glucose cotransporter-2 inhibitors, is paramount

Additionally, as weve alluded to, a more stepwise approach, which we think is still appropriate, both clinically as well as from a value perspective, delivers reductions in utilization as compared to an unmanaged environment

Isotretinoin (Accutane) was also often prescribed to address chronic acne
This allows for flexibility in dosing and can address specific patient concerns, such as allergies to certain components of commercial medications

1) Efficacy domains: what improves preclinically vs
