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Results from a 5-week multiple ascending dose trial performed at our institution in insulin treated adults with type 2 diabetes supports a safe and well tolerated once-weekly administration at clinically relevant dose levels

This lifts the subcutaneous fat away from the underlying muscle and creates a thicker target for the needle

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GLP-1 receptor agonists caused thyroid C-cell tumors, including medullary thyroid carcinoma, in rodent studies

validated, alarmed freezer storage is required in trial settings