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GLP-1RAs such as liraglutide and exenatide decrease pro-inflammatory cytokines, tumor necrosis factor-alpha ( TNF- ), and interleukin-1 (IL-18) in rodent mouse models of diabetic neuropathy [69,70]

The potential immunomodulatory effects discussed in this study are hypothetical and were not directly measured

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The supernatant was taken to bind with amylose resin for 2 h at 4 C

National Institute on Drug Abuse

It also offers a useful roadmap for future randomized trials, mechanistic work, and subgroup analyses designed to identify who benefits most and which outcomes are most responsive