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52,53 The improvement of antioxidant stress through GLP-1 signaling seems to be related to the activation of the GLP-1 R/cAMP/PKA signaling pathway and nuclear factor erythroid 2-related factor 2/heme oxygenase 1 signaling pathway

Pharmacological intervention decreases the risk of obesityrelated complications such as cardiovascular disease and hypertension [41, 42]

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Following our initial search, we identified five additional articles which met our inclusion criteria, bringing the total to 46 studies which were included in this review

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