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These are fundamentally different approaches to blood sugar management, with different side effect profiles, different effects on body weight, and different implications for long-term health

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Meissner WG, Remy P, Giordana C et al (2024) Trial of lixisenatide in early Parkinsons disease

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The FDA approved the use of semaglutide to decrease the risk of kidney failure and disease progression, as well as death from cardiovascular disease in adults with type 2 diabetes and chronic kidney disease in January 2025 based on outcomes of the FLOW trial [130]

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