retatrutide nejm 2023 obesity trial ly3437943 just posted the biggest weight-loss numbers ever recorded for a drug — 28.3% (≈70 lb) average in Phase 3, with 45% of people hitting 30%+ loss, territory once reserved for bariatric Retatrutide: Phase 3 Results (Up
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In clinical practice, unique factors often drive therapeutic decisions that are made by patients, HCPs, or both
Approximately 24 weeks following the standard titration schedule, assuming the medication is well-tolerated at each step
ICP is observed to rise progressively overnight in IIH
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The increased sympathetic tone may explain a known GLP-1RA class effect of a modest but significant increase in heart rate, the clinical consequences of which are undetermined
