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Compared to semaglutide alone, the combination resulted in significantly greater weight loss, better body composition, and reductions in visceral fat and inflammation

Until then, clinicians should individualize therapy and monitor closely for adverse effects.

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NICE has backed use of the Wegovy (semaglutide) for people with a body mass index (BMI) of 35 kg/m2 or more and at least one weight-related ailment such as high blood pressure, high cholesterol or diabetes as part of a weight management programme involving exercise and a reduce-calorie diet.