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Simultaneously, depletion of intracellular GSH, dysregulation of Nrf2 signaling, and iron-dependent lipid peroxidation weaken endogenous defenses, promoting neuronal death and contributing to ferroptosis pathways

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As with most RTKs, IGF-1R acts as a node in a complex web of robust signaling networks [72, 73]

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den Besten G, Bleeker A, Gerding A, van Eunen K, Havinga R, van Dijk TH, et al

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J.DickR

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