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Research often focuses on diabetics, leaving a gap in understanding their effects on non-diabetic individuals with overweight or obesity

People with hypothyroidism can use GLP-1 medications like semaglutide, but thyroid function requires close monitoring during weight loss treatment

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Effect of Semaglutide for Weight Management on Blood Pressure in Adults with Uncontrolled Hypertension and Overweight/Obesity: A Post Hoc Analysis from the STEP and OASIS Programs

Furthermore, the natriuretic action of SDF-1 occurs primarily in the distal tubules, where it cannot utilize tubuloglomerular feedback to modulate the deleterious effects of glomerular hyperfiltration