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To assess if CD8+ TILs are essential for the anticancer benefit imparted by tirzepatide treatment in the context of obesity, we depleted CD8+ T cells in vehicle-treated mice on the control diet, vehicle-treated DIO mice, and tirzepatide-treated DIO mice, all bearing MC38 tumors

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If testosterone is confirmed low, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) should be measured to differentiate primary from secondary hypogonadism

While generally well tolerated, some individuals may experience mild discomfort, injection site pain, dizziness, or shortness of breath

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