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Emergency surgeries carry higher risk than elective procedures because there's no time to adjust fasting protocols

MN: Just like any other medication, GLP-1s may not work the same way for everyone

The increased energy expenditure from glucagon activation may help preserve lean mass compared to approaches that rely primarily on appetite suppression, though this hypothesis requires further study

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Early Phase 2 trial data suggests this triple mechanism produces the most aggressive weight loss of any pharmaceutical approach to date, with some dose groups achieving over 24% body weight reduction in 48 weeks

10.1007/BF02427280 [DOI] [PubMed] [Google Scholar] Orskov, C
