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FEBS Lett 211(2):169174 Holter MM, Saikia M, Cummings BP (2022) Alpha-cell paracrine signaling in the regulation of beta-cell insulin secretion

For patients already managing multiple daily medications, once-weekly injection of tirzepatide can be more convenient and easier to use on a long-term basis

The prescribing population included 2,227,978 patients, representing 9,376,370 GLP-1 prescriptions between January 2024 and February 2026

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So, these therapies may be useful for patients who are overweight or obese and have higher insulin requirements. Advertisement A major strength of the analysis is its size and real-world design