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These can include nausea, vomiting, diarrhea, or constipation
Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are one of the most effective treatments for obesity

The mechanisms by which GLP-1 receptor agonists induce natriuresis are unclear, but in both rodents and humans, GLP-1 receptor agonist infusion enhances kidney lithium clearance, a marker of proximal tubular sodium reabsorption, as well as urinary pH

Weight usually follows
Contact your doctor if you cannot keep fluids down for more than 24 hours, if you experience severe abdominal pain, if you have a heart rate above 100 beats per minute at rest, or if you feel significantly worse after day four rather than better

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