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Palpitations / reflex tachycardia Fatigue Less Common Side Effects Nausea, abdominal pain Sleep disturbances Muscle cramps or joint pain Gingival hyperplasia (gum overgrowth, rare but possible with chronic use) Serious (but Rare) Side Effects Severe hypotension Arrhythmias (very rare) Allergic reactions (rash, itching, swelling) Liver dysfunction (rare, but check if jaundice or dark urine develops) Key Point for Patients Most frequent complaint = ankle edema

Selenium: may decrease the formation of proinflammatory cytokines, may contribute, in synergy with antithyroid drugs, to the stabilization of the autoimmune process in Graves' Disease and alleviation of Thyroid Eye Disease