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15 demonstrating powerful inhibition of food intake after ICV administration of GLP-1, an effect that could be blocked by the specific receptor antagonists exendin 939, which also enhanced spontaneous as well as neuropeptide Y-stimulated food intake

WARNING Compounded tirzepatide usage has been associated with the potential development of thyroid tumors, including thyroid cancer

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Mens Health Considerations No contraindications specific to male reproductive health exist, though long-term effects on spermatogenesis and endocrine parameters require further evaluation