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Professor Ania Jastreboff, MD, PhD Yale University provided an overview #ADA2026 of the TRIUMPH-1 trial for Retatrutide, the investigational triple G medicine from Eli Lilly and Company The unique trial design provided insights beyond #weightloss #obesity and also encompassed relevant endpoints for co-morbidities such as knee osteoarthritis and obstructive sleep apnea, two comorbidities highly sensitive to weight loss

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Adding SS-31 while the loop is still running may slow the descent, but the inputs are still accelerating the damage faster than any compound can address it

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Collectively, these findings explain how GLP-1, despite acting to simultaneously enhance insulin biosynthesis and secretion, maintains functional cell mass through attenuation of ER stress
