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Whilst GLP-1 agonists are not licensed for treating depression and evidence remains preliminary, their effects on brain regions involved in mood regulation have sparked considerable scientific interest

Saint-Maurice PF, Troiano RP, Bassett DR et al (2020) Association of daily step count and step intensity with mortality among US adults

There were fewer serious adverse events and serious cardiac disorders in participants receiving semaglutide vs placebo irrespective of AF history (Supplemental Table 2)

10.1038/nm919 36 EngJ.KleinmanW

Lindicazione terapeutica da parte dellEMA (European Medicines Agency) comprende gli adulti con BMI 30 kg/m (obesit) o con BMI 27 kg/m (sovrappeso) in presenza di comorbidit associate al peso corporeo, quali ipertensione arteriosa, dislipidemia o diabete di tipo 2