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Nimacimab + tirzepatide combination results in 30% weight loss owenhaskins Apr 16, 2025 3 min read Skye Bioscience's novel CB1 antibody, nimacimab in combination with the dual GLP-1/GIP agonist, tripeptide, resulted in greater than 30% weight loss

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Zepbound works by activating both GLP-1 and GIP receptors

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By stimulating insulin secretion and reducing glucagon release, GLP-1 RAs lower blood sugar levels

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Patients should never attempt to self-treat diabetes or obesity without professional guidance

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16.1% on placebo) Diarrhea: 29.7% (vs

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Clinically known as glucagon-like peptide 1 agonists , GLP-1s were originally developed to treat diabetes

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