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Human GLP-1RHaloTag and NanoLuc-ARRB2 fusion constructs were used for the measurement of -arrestin recruitment with NanoBRET technology (47)

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However, there was no clear explanation for the neutral cardiovascular profile of lixisenatide, rather than the expected cardioprotective effect

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The ongoing Exenatide-PD3 phase 3 trial aims to provide more definitive evidence on whether these drugs can slow Parkinson's progression