glp-1 how it works Medications Infographic Mechanisms of action of GLP-1RA.
Description
The duration of action fundamentally distinguishes these agents' clinical utility
It is a 42-amino acid peptide secreted by the K-cells, present in high density in the duodenum and upper jejunum, following oral ingestion of nutrients such as glucose, amino acids, and long-chain fatty acids (Fig
GLP-1 also stimulates insulin gene transcription and islet cell growth
Harreiter J, Just I, Leutner M, Bastian M, Brath H, Schelkshorn C, et al
doi: 10.1016/j.cmet.2023.11.009 99 WongCKYustaBKoehlerJABaggioLLMcLeanBAMatthewsDet al
GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring FGF7
