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There is limited data about exactly how GLP-1 RAs affect fertility, pregnancy, and breastfeeding

While medications help control hunger and cravings, long-term success often comes from pairing treatment with improved nutrition habits and physical activity

Search Strategy We searched PubMed, Embase and the Cochrane Central Register of Controlled Trials (CENTRAL) databases from their inception up until 31st July 2023 for clinical trials that compared once weekly tirzepatide (5, 10 and 15 mg) with placebo or GLP-1 RAs in adults with overweight or obesity

While the evidence is still unsettled, some people with irritable bowel syndrome (IBS) may find digestive enzymes helpful for managing their symptoms

Well also touch on a few of the strategies Ive seen people trying in real life as they move forward without the medication

Over time, this leads to: Increased hunger and overeating Blood sugar dysregulation Insulin resistance Weight gain and difficulty losing fat Boosting GLP-1 activity can be a powerful strategy for individuals dealing with metabolic syndrome, prediabetes, or stubborn weight
