glp 1 negative side effects Adverse of GLP-1 Receptor Agonists GLP-1s 101: What the science

One meta-analysis involving patients with T2D without cardiovascular disease found a reduction in MACE associated with SGLT2i regimens of (adjusted pooled OR and 95% CI) 0.82 (0.730.92), with GLP1-RAs regimens of 0.93 (0.811.06), and with combined therapy of 0.70 (0.500.98)

Countries without their own HTA may partially defer to NICE for value benchmarks or at least consider NICEs published cost/QALY figures

Waiting times vary by region

If your plan covers weight loss medications at all, the next step is often figuring out which drugs are preferred and what documentation is required

doi: 10.1016/0014-5793(86)81429-6 31 CalannaSChristensenMHolstJJLaferrreBGluudLLVilsbllTet al

95% CI 1.643.18 versus RR, 1.27